Product ID:FREON 23
MSDS Date:07/10/1997
FSC:NIIN:Submitter:N EN
Status Code:A
MSDS Number: CLHKK

Emergency Phone: 800-441-3637

Info Phone: 800-441-7515;800-441-9442

Cage: 18873

Telephone: 800-441-7515;800-441-9442

Cage: 18873

METHANE, TRIFLUORO-. (CHF3)

CAS: 75-46-7

RTECS: PB6900000

OSHA PEL NONE ESTABLISHED

ACGIH TLV: NONE ESTABLISHED

Routes of Entry: Inhalation:YES Skin:YES Ingestion:NO
Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO
Health Hazards Acute and Chronic:CHLOROFLUOROCARBON (CFC) AND
FLUOROCARBON MATERIALS HAVE PRODUCED SENSITIZATION OF THE
MYOCARDIUM TO EPINEPHRINE IN LABORATORY ANIMALS AND COULD HAVE A
SIMILAR EFFECT IN HUMANS. THE USE OF EPINEPHRINE MAY BE
CONTR-INDICATED EXCEPT FOR LIFE SUSTAINING USES IN HUMANS ACUTELY
OR CHRONICALLY EXPOSED TO FLUORINATED HYDROCARBONS . POTENTIAL
HEALTH EFFECTS: INHALATION OF HIGH CONCENTRATIONS OF VAPO R IS
HARMFUL AND MAY CAUSE HEART IRREGULARITIES, UNCONSCIOUSNESS, OR
DEATH. INTENTIONAL MISUSE OR DELIBERATE INHALATION MAY CAUSE DEATH
WITHOUT WARNING. VAPOR REDUCES OXYGEN AVAILABLE FOR BREATHING AN D
IS HEAVIER THAN (EFTS OF OVEREXPOS)
Explanation of Carcinogenicity:NONE OF THE COMPONENTS PRESENT IN THIS
MATERIAL AT CONCENTRATIONS EQUAL TO OR GREATER THAN 0.1% ARE LISTED
BY IARC, NTP, OSHA OR ACGIH AS A CARCINOGEN.
Effects of Overexposure:HEALTH HAZARD ACUTE AND CHRONIC (CONT'D): THAN
AIR. LIQUID CONTACT CAN CAUSE FROSTBITE. HUMAN HEALTH EFFECTS:
OVEREXPOSURE BY INHALATION MAY INCLUDE NONSPECIFIC DISCOMFORT SUCH
AS NAUSEA, HEADACHE, O R WEAKNESS; TEMPORARY NERVOUS SYSTEM
DEPRESSION WITH ANESTHETIC EFFECTS SUCH AS DIZZINESS, HEADACHE,
CONFUSION, INCOORDINATION, AND LOSS OF CONSCIOUSNESS; OR WITH GROSS
OVEREXPOSURE (>20%), POSSIBLY T EMPORARY ALTERATION OF THE HEART'S
ELECTRICAL ACTIVITY WITH IRREGULAR PULSE, PALPITATIONS, OR
INADEQUATE CIRCULATION. EYE OR SKIN CONTACT WITH THE LIQUID MAY
CAUSE FROSTBITE.
Medical Cond Aggravated by Exposure:INDIVIDUALS WITH PREEXISTING
DISEASES OF THE CENTRAL NERVOUS OR CARDIOVASCULAR SYSTEM MAY HAVE
INCREASED SUSCEPTIBILITY TO THE TOXICITY OF EXCESSIVE EXPOSURES.

First Aid:INHALATION: IMMEDIATELY REMOVE TO FRESH AIR. KEEP PERSON
CALM. CALL A PHYSICIAN. IF NOT BREATHING, GIVE ARTIFICIAL
RESPIRATION. IF BREATHING IS DIFFICULT, GIVE OXYGEN. SKIN CONTACT:
FLUSH WITH WATER. TREAT FOR FORSTBITE IF NECESSARY BY GENTLY
WARMING AFFECTED AREAS. EYE CONTACT: IN CASE OF LIQUID CONTACT,
IMMEDIATELY FLUSH EYES WITH PLENTY OF WATER FOR 15 MINUTES. CALL A
PHYSICIAN. INGESTION: CONT ACT A PHYSICIAN IMMEDIATELY . NOTES TO
PHYSICIANS: BECAUSE OF POSSIBLE DISTURBANCES OF CARDIAC RHYTHM,
CATECHOLAMINE DRUGS, SUCH AS EPINEPHRINE, SHOULD BE CONSIDERED ONLY
AS A LAST RESORT IN LIF E-THREATENING EMERGENCIES.

Flash Point:WILL NOT BURN.
Autoignition Temp:=765.C, 1409.F
Lower Limits:N/APPLICABLE
Upper Limits:N/APPLICABLE
Extinguishing Media:AS APPROPRIATE FOR COMBUSTIBLES IN AREA.
Fire Fighting Procedures:USE WATER SPRAY OR FOG TO COOL CONTAINERS.
WEAR NIOSH APPROVED PRESSURE DEMAND SCBA AND FULL PROTECTIVE
EQUIPMENT . ACTUAL AUTOIGNITION TEMPERATURE (AIT) CAN BE AFFECTED
BY THE CONCENTRATION OF VAPORS & OXYGEN, VAPOR/AIR CONTACT TIME,
PRESSURE, VOLUME, CATALYTIC IMPURITIES, ETC. PROCESS CONDITIONS
(SUPP SAFETY)
Unusual Fire/Explosion Hazard:THERMAL DECOMPOSITION PRODUCTS MAY
INCLUDE FLUORIDES . CYLINDERS ARE EQUIPPED WITH TEMPERATURE AND
PRESSURE RELIEF DEVICES BUT MAY STILL RUPTURE UNDER FIRE
CONDITIONS. DECOMPOSITION MAY OCCUR, P RODUCING HF, CO AND POSSIBLY
COF2. AUTODECOMPOSITION: NOT DETERMINED.

Spill Release Procedures:REVIEW FIRE FIGHTING AND HANDLING SECTIONS
BEFORE PROCEEDING WITH CLEAN-UP. USE APPROPRIATE PERSONAL
PROTECTIVE EQUIPMENT DURING CLEAN-UP. MATERIAL EVAPORATES AT
ATMOSPHERIC PRESSURE (VAPORIZES). VENT ILATE AREA, ESPECIALLY LOW
PLACES WHERE HEAVY VAPORS MIGHT COLLECT. REMOVE OPEN FLAMES. WEAR
NIOSH-APPROVED SELF-CONTAINED BREATHING APPARATUS (SCBA) FOR LARGE
SPILLS OR WHEN RELEASE OCCURS.

Handling and Storage Precautions:HANDLING: AVOID BREATHING HIGH
CONCENTRATIONS OF VAPOR. AVOID CONTACT OF LIQUID WITH EYES AND
PROLONGED SKIN EXPOSURE. USE WITH SUFFICIENT VENTILATION TO KEEP
EMPLOYEE EXPOSURE BELOW RECOMMENDED LIMIT S. STORAGE: CLEAN, DRY
AREA. DO NOT HEAT ABOVE 51.7 DEG C (125 DEG F).
Other Precautions:NO SMOKING IN AREA OF USE. DO NOT USE IN THE VICINITY
OF ARC WELDING, OPEN FLAMES OR HOT SURFACES. HEAT AND/OR UV
RADIATION MAY CAUSE THE FORMATION OF FLUORIDES .

Respiratory Protection:NIOSH APPROVED RESPIRATOR APPROPRIATE FOR THE
EXPOSURE OF CONCERN . UNDER NORMAL MANUFACTURING CONDITIONS, NO
REPIRATORY PROTECTION IS REQUIRED WHEN USING THIS PRODUCT.
SELF-CONTAINED BREATHING APPARATUS (SCBA) IS REQUIRED IF A LARGE
SPILL OR RELEASE OCCURS.
Ventilation:NORMAL VENTILATION FOR ROUTINE MANUFACTURING PROCEDURES IS
GENERALLY ADEQUATE. LOCAL EXHAUST SHOULD BE USED WHEN LARGE AMOUNTS
(OTHER PROT EQUIP)
Protective Gloves:IMPERVIOUS GLOVES SHOULD BE USED WHEN HANDLING
LIQUID.
Eye Protection:ANSI APPROVED CHEMICAL SAFETY GOGGLES SHOULD BE WORN.
Other Protective Equipment:EYEWASH AND DELUGE SHOWER MEETING ANSI
DESIGN CRITERIA . VENTILATION (CONT'D): ARE RELEASED. MECHANICAL
VENTILATION SHOULD BE USED IN LOW OR ENCLOSED PLACES.
Supplemental Safety and Health
FIRE FIGHT PROC (CONT'D): SHOULD BE ANALYZED TO DETERMINE IF THE AIT'S
MAY BE HIGHER OR LOWER. CYLINDERS ARE EQUIPPED WITH TEMPERATURE &
PRESSURE RELIEF DEVICES BUT MAY STILL RUPTURE UNDER FIRE CONDIT
IONS. DECOMPOSITION MAY OCCUR, PRODUCING HF, CO & POSSIBLY COF2.
AUTODECOMPOSITON: NOT DETERMINED. (ECOLOGICAL)

Boiling Pt:=-82.1C, -115.6F
Vapor Pres:686 PSIG @25 DEG C (77 F)
Vapor Density:2.4 AIR=1
Solubility in Water:0.1 WT% @ 25C (77F).
Appearance and Odor:CLEAR, COLORLESS COMPRESSED GAS OR LIQUIFIED GAS.
SLIGHT ETHEREAL ODOR.
Percent Volatiles by Volume:100%

Stability Indicator/Materials to Avoid:YES
INCOMPATIBLE WITH ALKALI OR ALKALINE EARTH METALS - POWDERED AL, ZN,
BE, ETC.
Stability Condition to Avoid:AVOID OPEN FLAMES AND HIGH TEMPERATURES.
Hazardous Decomposition Products:DECOMPOSITION PRODUCTS ARE HAZARDOUS.
THIS MATERIAL CAN BE DECOMPOSED BY HIGH TEMPERATURES (OPEN FLAMES,
GLOWING METAL SURFACES, ETC.) FORMING HF, COF2, OR CO. FLUORIDES .
Conditions to Avoid Polymerization:WILL NOT OCCUR.

Waste Disposal Methods:RECLAIM BY DISTILLATION OR REMOVE TO PERMITTED
WASTE FACILITY. DISPOSE OF IN ACCORDANCE WITH ALL FEDERAL, STATE,
AND LOCAL REGULATIONS.

Toxicological Information:ANIMAL DATA: INHALATION 4-HOUR LC50: >663,000
PPM IN RATS. HFC-23 IS UNTESTED FOR SKIN & EYE IRRITANCY, & FOR
ANIMAL SENSITIZATION. EFFECTS FROM SINGLE HIGH INHALATION TO HFC-23
INCLUDE ANESTHETIC EFF ECTS, AND NON SPECIFIC EFFECTS SUCHAS WEIGHT
LOSS WERE OBSERVED AT CONCENTRATIONS >22%. NO CARDIAC SENSITIZATION
WAS OBSERVED IN DOGS AFTER BREATHING 800,000 PPM FOR PERIODS OF
5-10 MINUTES FOLLOWING EPINEPHRINE CHALLENGE. IN ANOTHER TEST,
DOGS EXPOSED TO UP TO 30% OR UP TO 50% (WITH ADDITIONAL OXYGEN),
HAD NO POSITIVE RESPONSES. NO CARDIAC SENSITIZATION OCCURRED IN
BABOONS EXPOSED BY INHALATION T O 10%, 30%, 50%, OR 70% (STATE
REG)

Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.

Ecological:N/P. SUPPLEMENTAL SAFETY (CON'T): DUPONT FIRE EMERGENCY
EXPOSURE LIMITS (FEEL) ARE ESTABLISHED TO FACILITATE THE SAFE
RELEASE OF A FIRE EXTINGUISHANT INTO SPACES NORMALLY OCCUPIED BY
PEOPLE TO EXTI NGUISH A FIRE OR PREVENT AN EXPLOSION AND SPECIFY
AIRBORNE CONCENTRATIONS OF BRIEF DURATIONS WHICH SHOULD NOT RESULT
IN PERMANENT ADVERSE HEALTH EFFECTS OR INTERFERE WITH ESCAPE. FOR
MORE INFORMATION ON THE APPLICABLILITY OF FEEL'S, CONTACT DUPONT.
THE DUPONT FIRE EMERGENCY EXPOSURE LIMIT (FEEL) FOR THIS MATERIAL
IS 20% V/V FOR UP TO 15 MINUTES WITH A 1 MINUTE NOT-TO-EXCEED
CEILING OF 23% V/V.

Transport Information:SHIPPING INFORMATION: DOT/IMO/IATA: PROPER
SHIPPING NAME: TRIFLUOROMETHANE. HAZARD CLASS: 2.2. UN NO.: 1984.
DOT/IMO LABEL: NONFLAMMABLE GAS. SHIPPING CONTAINERS: CYLINDERS,
TON TANKS, TANK TRUCKS.

SARA Title III Information:TITLE III HAZARD CLASSIFICATION SECTIONS
311, 312: ACUTE: YES. CHRONIC: NO. FIRE: NO. REACTIVITY: NO.
PRESSURE: YES. HAZARDOUS CHEMICAL LISTS: SARA EXTREMELY HAZARDOUS
SUBSTANCE: NO. SARA TOXIC CHEMIC AL: NO.
Federal Regulatory Information:TSCA INVENTORY STATUS:
REPORTED/INCLUDED. HAZARDOUS CHEMICAL LISTS: CERCLA HAZARDOUS
SUBSTANCE: NO.
State Regulatory Information:N/P. TOXICOLOGICAL (CONT'D): HFC-23
BEFORE OR AFTER AN EPINEPHRINE CHALLENGE; THERE WAS A DOSE-RELATED
DECREASE IN HEART RATES AND DIFFERENCES IN REPSIRATORY RATES DURING
EXPOSURE. NO ANIMAL TESTS A RE AVAILABLE TO DEFINE THE CARCINOGENIC
HAZARDS OF HFC-23. THE MATERNAL AND DEVELOPMENTAL NOAEL WAS 50,000
PPM. HFC-23 IS NOT CONSIDERED A UNIQUE DEVELOPMENTAL HAZARD TO THE
CONCEPTUS. THERE WERE NO D EVELOPMENTAL OR REPRODUCTIVE EFFECTS.
TESTS HAVE SHOWN THAT HFC-23 DOES NOT PRODUCE GENETIC DAMAGE I N
BACTERIAL OR MAMMALIAN CELL CULTURES. IT HAS NOT PRODUCED GENETIC
DAMAGE IN TESTS ON ANIMALS.